Trace elements deficiency

Trace elements: account for only 0.02% of the total body weight but their role is many times more important

Trace elements are now possible to measure

Common definition of trace elements is: Elements which are detected in small but not precisely known amounts in the living body, required to perform vital metabolic activities in organism.

Recent advances in analytical technologies have made it possible to measure these elements precisely and to determine their functions and the characteristics of their deficiency and excess. Nowdays, trace element deficiencies are often encountered clinically, especially in connection with congenital abnormalities, reduced anti-oxidant potential in organisms, accelerated aging, developmental retardation, abnormal pregnancies and lifestyle-related diseases,

Essential trace elements of human organism

Essential trace elements of the human body are:

·      zinc (Zn), you can find in oysters, red meat, poultry

·      copper (Cu), you can find in oysters, nuts, seeds, shitake, lobster, liver, dark chocolate

·      selenium (Se), you can find in pork, beef, turkey, chicken, fish, shellfish, eggs 

·      chromium (Cr), you can find in broccoli, liver, brewer’s yeast, potatoes, whole grains, seafood

·     cobalt (Co), you can find in red meat, milk, fish, cabbage, figs, turnips

·      iodine (I), you can find in seaweed, dairy, tuna, shrimp, eggs, table salt

·      manganese (Mn), you can find in whole grains, clams, oysters, mussels, nuts, soybeans, rice, leafy vegetables, coffee, tea and

·      molybdenum (Mo), you can find in peas, lentils, grains, fruits, vegetables, milk, cheese, animal organs, the water.

They play significant roles as active centers of enzymes or as trace bioactive substances.

Like vitamins, trace elements were also originally conisdered as nutrients. However, they also may have pharmacological actions if taken in amounts several times higher than the nutritional requirements. However, when taking trace elements, caution must be exercised to avoid excessive dosage!

It is interesting that over the long history of humankind, healthy dietary styles established supply appriopriate levels of trace elements and deficiencies are unlikely to occur unless the appropriate diet is eaten, the dietary patterns change dramatically, or the metabolism of trace elements is disturbed. Both deficiency and excess of trace elements are either congenital or acquired.

Trace elementMajor related enzymesConcerned metabolism
ZincCarbonic anhydrase,  Peptidase,  Alcohol dehydrogenase,  Alkaline phosphatase,  PolymeraseProteins, Lipids, Carbohydrates, Bones
Copper  Monoamine oxidase,  Cytochrome oxidase,  Ascorbic acid oxidase,  Dopamine-hydroxylase,  Superoxide dismutaseHemopoiesis  Bones, Connective tissues
Chromium Glucose tolerance factor Carbohydrates, Cholesterol, Connective tissues, Proteins
Selenium Glutathione peroxidase,  (GSH-Px)  5 -deiodinase (type I),  Various selenoproteins Antioxidant action  T4 T3 conversion, Reduced carcinogenicity  action 
Manganese Arginase,  Pyruvate carboxylase,  Superoxide dismutase,  Glycosyltransferase Bones, Carbohydrates, Lipids, Reproduction,  Immunity 
Molybdenum Xanthine oxidase,  Xanthine dehydrogenase,  Aldehyde oxidase,  Nitrous acid oxidase Amino acids, Uric acids,  Sulfuric acids
Cobalt Vitamin B Hemopoiesis 
Iodine Thyroid hormone Tissues
Trace elements importance in your body

Trace elements deficiency

A major outcome of trace element deficiencies is reduced activity of the concerned enzymes. As each trace element is related to so many enzymes, deficiency of a single trace element is often not associated with any specific clinical manifestations, but rather expresses as a combination of various symptoms. Therefore it is often difficult for clinicians to identify deficiencies of some particular trace elements. Trace element deficiency is one of the most difficult conditions to diagnose.

Trace  element Symptoms of deficiency
Zinc Gradually exacerbating  eruptions, stomatitis, glossitis, alopecia,  nail changes, diarrhea, vomiting, delayed wound healing, growth retardation, immunosuppression, taste disorder, anorexia 
Copper Anemia,  leukopenia, neutropenia  bone changes (children) – bone radiolucency,  bone cortex thinning …
Chromium Abnormal glucose tolerance, reduced respiratory quotient, weight loss, peripheral neuropathy, increased serum free fatty acids, abnormal nitrogen balance…
Selenium Myalgia, cardiomyopathy (e.g.  fibrosis), white nail bed
Manganese Reduced serum cholesterol, reduced coagulation, hair reddening, dermatitis, growth retardation
Molybdenum Tachycardia, night blindness, scotoma, irritability, somnolence, disorientation, coma 
Cobalt Pernicious anemia, methylmalonic acidemia 
Iodine Goiter, hypothyroidism 
Symptoms of deficiency of trace elements

The most common causes of trace elements deficiency include congenital metabolic disorders, unbalanced nutrition, diet poor in trace elements, chelating drugs, surgery, pregnancy, excessive alcohol consumption, liver disease and nephropathy.

Trace elements exess

An excessive intakeof trace elements may casue the toxicity. The toxicity is a matter of dose or exposure.

Trace  element Symptoms of excess
Zinc Relative Fe-Cu deficiency,  nausea, vomiting,  abdominal pain, melena,  hyperamylasemia,  somnolence, hypotension,  lung edema, diarrhea, reduced reproductive  function,  taste disorder, hyposmia,  anemia 
Copper Nausea, vomiting,  heartburn, diarrhea, hemoglobinuria,  hematuria, oliguria,  anuria, hypotension, coma,  melena 
Chromium Nausea, vomiting,  peptic ulcer, CNS disorder,  liver/kidney dysfunction,  growth retardation 
Selenium alopecia, nail  detachment, CNS disorder
Manganese Parkinsonian syndrome, impotence, loss of vigor,  somnolence, anorexia,  edema, myalgia, headache,  excitation, fatigue…
Molybdenum Hyperuricemia, gout 
Cobalt Cobalt poisoning 
Iodine Goiter, hypothyroidism 
Symptoms of exsess of trace elements

Supplementing trace elements

Provided you have been diagnosed with trace elements deficiency you can change your diet and include the food containing the respective trace elemnt or you can start to take dietary supplements such as MITRACELL from For Long Life.

Allways follow the instruction as the excessive ingestion of trace elements may be dangerous.

Leave a Reply

Let's live a long life with us

3505 S Ocean Dr

Hollywood 33019, FL

United States

Follow Us Now