If your skin has brown spots it can be from too much iron and lipofuscin.
Have you ever looked at the back of someone's hands and seen age spots? When you see these age spots, you are probably looking at lipofuscin. Lipofuscin is a brownish pigment made from waste products. Sometimes they're called liver spots or age spots. But did you know they are present throughout the human body? The ones on the skin are the ones you can see, but they permeate the entire body – especially important organs in the brain. In a study, they found that lipofuscin creates a runaway process where a little bit creates more, Lipofuscin incorporates iron in its formation, and iron generates massive amounts of free radicals. It's possible that lipofuscin is a protection mechanism of the body against excess iron. We know that the body will try to protect itself, and excess iron is dangerous. In fact, if you deplete your iron short of anemia, you may age less fast.
THIS CHARACTERISTIC OF LIPOFUSCIN MAY CONTRIBUTE TO AN INCREASED LEVEL OF RADICAL FORMATION AND OXIDATIVELY MODIFIED CELLULAR COMPONENTS SUCH AS PROTEINS, LIPIDS, AND RNA/DNA, WHICH HAS BEEN SHOWN TO BE EXTENSIVE IN AGING CELLS.
And lipofuscin could be part of the body's response to the excess iron. But the lipofuscin is dangerous. It's worse when it's in the brain, affecting the nerve cells in a very bad way. To fully understand this research, you will need to know something about brain cells. They're most powerful when they can acquire signals from other brain cells simultaneously. It's like a pianist -- if you play with all ten fingers, you can play a variety of chords. While a pianist who only plays with one finger can only play notes. Lipofuscin works against your brain's ability to receive signals as chords. It inhibits the nerve cells from processing more than one signal. Lipofuscin makes nerve cells unefficient It builds up in the nerve cells, creating more and more of these stupid nerve cells. Then all of these cells are piled up in the human brain This may result in dementia or Alzheimer's.
THE CORTEX WITH THE HIGHEST PERCENTAGE OF LIPOFUSCIN-CONTAINING NEURONS HAD THE LOWEST MULTIPLE-UNIT SIGNALS WHILE THE CORTEX WITH THE LOWEST PERCENTAGE OF LIPOFUSCIN-CONTAINING NEURONS HAD THE HIGHEST NUMBER OF MULTIPLE-UNIT SIGNALS.
Finally, this very interesting study shows how you can prevent lipofuscin doing its damage. The potential key is - again - the vitamin known as RIBOFLAVIN Unfortunately this study was done on fruit flies cells, and some scientific sources out of the medicinal and pharma world will claim it may not apply to people. But it probably does. You might want to consider increasing your consumption of riboflavin. Nevertheless it will probably do because fruit flies have a extremely identical cell turnover compared to humans. One of the reasons fruit flies have a short life span is lipofuscin and fruitflies that got riboflavin .....Lived longer !!!
Personal conclusion : Iron creates lipofuscin very easily, and it probably contributes to premature aging. In combination with other anti aging products as for instance astragenol* that keeps cells alive by blocking the shortening the telomeres you have a potential tool to delay the aging process and reach old age in a still quality of life situation.
Prof.Guy Van Elsacker Dr.Sc.